Bioinformatics: Genetics 101

Help Me Understand Genetics presents basic information about genetics in clear language and provides links to online resources. Genetics Home Reference is a service of the U.S. National Library of Medicine, part of the National Institutes of Health, an agency of the Department of Health and Human Service

Excellent tutorials to bring you up to speed on bioinformatics & cell biology.

From Nature Group. Topics include Cell Biology, Genetics, Ecology and more.

bioinformatics basics - University College London

Classical and molecular genetics; DNA as the genetic material; Central dogma (DNA to RNA to protein); Gene regulation; Biotechnology

NCBI resources

Nature Publishing Group

Video

Video

Video

INTrons (non-coding sequences) INTerrupt coding sequences while EXons are EXpressed (translated into an amino acid sequence). Palindrome: a sequence reading the same in both directions, e.g. GACCAG. These are often sites at which restriction enzymes cleave DNA.

Transcrition/translation - Exons and introns. Courtesy: Cold Spring Harbor Laboratory

introns - see for other topics as well

Article in Brief Bioinform. 2005 Jun;6(2):118-34. free article

Paul Andersen explains how DNA replication ensures that each cell formed during the cell cycle has an exact copy of the DNA.

Courtesy: Michigan State University

Courtesy: University of California Museum of Paleontology

In this video Paul Andersen explains how the CRISPR/Cas immune system was identified in bacteria and how the CRISPR/Cas9 system was developed to edit genomes.

Jennifer Doudna (UC Berkeley / HHMI)

Jennifer Doudna | TED Talks

From Harvard Univ.

PeptideCutter predicts potential cleavage sites cleaved by proteases or chemicals in a given protein sequence.